About Prescient Therapeutics
Prescient’s universal CAR-T and targeted therapies are both personalised medicine approaches that seek to improve patient outcomes and provide new tools for clinicians in combating cancer.
PTX Raises $7 million via Strongly Supported Placement
Prescient Therapeutics (ASX: PTX) is pleased to announce that it has received firm commitments to raise $7,046,084 (before costs) by way of a share placement (Placement) to professional and sophisticated investors of 128,110,611 fully paid ordinary shares (Placement Shares) at $0.055 (5.5 cents) per share, being the same issue price as the recently completed Share Purchase Plan (SPP)…
CAR-T is a cell therapy which works by genetically modifying a patient’s own T-cells by adding a new receptor (CAR) to recognise cancer antigens. CAR-T therapy has achieved stunning success in certain blood cancers. However, conventional CAR-T also faces considerable challenges that limit their broader use, including manufacturing, safety and adaptability. The OmniCAR platform seeks to overcome these challenges. OmniCAR is a modular, universal CAR platform using technology exclusively from CAR-T pioneer the University of Pennsylvania (UPenn), as well as Oxford University. It has the potential to dramatically enhance the safety and efficacy of any CAR-T therapy, enabling in-house development of next-generation CAR-T therapies, and by dramatically improving external CAR-T programs it will create opportunities for collaboration and business development in the CAR-T field.
PTX - 100
PTX-100 is a first in class compound with the ability to block an important cancer growth enzyme known as geranylgeranyl transferase-1 (GGT-1), thereby disrupting the oncogenic Ras pathway. PTX-100 is currently in a novel basket Phase 1b study of cancers driven by Rho and Ras mutations.
PTX - 200
PTX-200 is a novel PH domain inhibitor that inhibits an important tumor survival pathway known Akt, which plays a key role in the development of many cancers, including leukemia; breast cancer and ovarian cancer.
Prescient Therapeutics has a broad pipeline of personalised cancer treatments, comprising CAR-T and targeted therapies, and spanning a range of different cancers. We have licensed technologies from, and also collaborates with, world-leading cancer centres in the United States as well as Australia.
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