About Prescient Therapeutics

Prescient’s universal CAR-T and targeted therapies are both personalised medicine approaches that seek to improve patient outcomes and provide new tools for clinicians in combating cancer.

Prescient receives new US Patent for Companion

Prescient Therapeutics (ASX: PTX) is pleased to announce that it has received a notice of allowance from the United States Patent and Trademark Office (USPTO) for a new patent covering methods for using a specific biomarker to stratify breast cancer patients and identify those most likely to respond to treatment with its anti-cancer compound PTX-100 (continue reading…)

Investor Briefing

Our Science

CAR-T Therapy

CAR-T is a cell therapy which works by genetically modifying a patient’s own T-cells by adding a new receptor (CAR) to recognise cancer antigens. CAR-T therapy has achieved stunning success in certain blood cancers.  However, conventional CAR-T also faces considerable challenges that limit their broader use, including manufacturing, safety and adaptability.  The OmniCAR platform seeks to overcome these challenges.  OmniCAR is a modular, universal CAR platform using technology exclusively from CAR-T pioneer the University of Pennsylvania (UPenn), as well as Oxford University.  It has the potential to dramatically enhance the safety and efficacy of any CAR-T therapy, enabling in-house development of next-generation CAR-T therapies, and by dramatically improving external CAR-T programs it will create opportunities for collaboration and business development in the CAR-T field.

PTX - 100

PTX-100 is a first in class compound with the ability to block an important cancer growth enzyme known as geranylgeranyl transferase-1 (GGT-1), thereby disrupting the oncogenic Ras pathway.  PTX-100 is currently in a novel basket Phase 1b study of cancers driven by Rho and Ras mutations.

PTX - 200

PTX-200 is a novel PH domain inhibitor that inhibits an important tumor survival pathway known Akt, which plays a key role in the development of many cancers, including leukemia; breast cancer and ovarian cancer. 


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Prescient Therapeutics is a clinical-stage oncology company developing personalised medicine approaches to cancer, including cellular and targeted therapies. The future of medicine is personal.


Prescient Therapeutics has a broad pipeline of personalised cancer treatments, comprising CAR-T and targeted therapies, and spanning a range of different cancers. We have licensed technologies from, and also collaborates with, world-leading cancer centres in the United States as well as Australia.


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Broker Report

The broker reports included on this page of the website have not been commissioned or endorsed by Prescient Therapeutics Limited (Prescient) or its officers and are provided for information purposes only. The information contained in these report is not produced by Prescient and is not intended to be investment or financial product advice given by Prescient. Prescient recommends recipients of the reports make their own assessment of Prescient before making any investment decision. Any inquiries with respect to the reports should be directed to the relevant issuer of the report.


CAR-T Super Girl

Laurie Adami has had a long and intricate journey with blood cancer, after being diagnosed with Non-Hodgkin Lymphoma in 2006. Over the next 12 years,…

CAR-T Super Girl

Laurie Adami has had a long and intricate journey with blood cancer, after being diagnosed with Non-Hodgkin Lymphoma in 2006. Over the next 12 years,…

Is “next-gen” CAR-T the beginning of the end of cancer?

Cancer is a word we all dread to hear yet a cure for the deadly disease has always felt so far away. However, thanks to…

Prescient Therapeutics – Interview with Dr Allen Ebens

In the battle against blood cancer, chimeric antigen receptor T cell (CAR-T) therapy is proving to be a shining light on the horizon. Dr Allen…

How CAR-T uses the body’s own immune system to fight cancer

Special Report: A form of immunotherapy that involves modifying a patient’s white blood cells so they recognise and target cancer cells is shaping up as…

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